Organoids — Preclinical Models of Human Disease

Mo Li, Ph.D., and Juan C. Izpisua Belmonte, Ph.D.

N Engl J Med 2019; 380:569-579 DOI: 10.1056/NEJMra1806175

 

A Balance between silencing foreign DNA and protecting self in Caenorhabditis elegans

Frokjaer-Jensen C

Curr. Op. Syst. Biol, 13, Feb 2019, 37-43

Selective interactions between diverse STEs organize the ANT-C Hox cluster

Mo Li, Zhibo Ma, Sharmila Roy, Sapna K. Patel, Derrick C. Lane, Carly R. Duffy & Haini N. Cai

Scientific Reports volume 8, Article number: 15158 (11 October 2018)

Epigenetic control of endocrine pancreas differentiation in vitro: current knowledge and future perspectives

Astro V., Adamo A.
Front. Cell Dev. Biol. | doi: 10.3389/fcell.2018.00141
 

Phenotypic and molecular consequences of step-wise temperature increase across generations in a coral reef fish.

Bernal MA, Donelson JM, Veilleux HD, Ryu T, Munday PL, Ravasi T.

Mol Ecol. 2018 Sep 29. doi: 10.1111/mec.1488

Nuclear localization and phosphorylation modulate pathological effects of Alpha-Synuclein.

Pinho R, Paiva I, Jercic KG, Fonseca-Ornelas L, Gerhardt E, Fahlbusch C, Garcia-Esparcia P, Kerimoglu C, Pavlou MA, Villar-Piqué A, Szego É, Fonseca TL, Odoardi F, Soeroes S, Rego AC, Fischle W, Schwamborn JC, Meyer T, Kügler S, Ferrer I, Attems J, Fischer A, Becker S, Zweckstetter M, Borovecki F, Outeiro TF.

Hum Mol Genet. 2018 Sep 13. doi: 10.1093/hmg/ddy326.

Finding Nemo’s Genes: A chromosome-scale reference assembly of the genome of the orange clownfish Amphiprion percula.

Lehmann R, Lightfoot DJ, Schunter C, Michell CT, Ohyanagi H, Mineta K, Foret S, Berumen ML, Miller DJ, Aranda M, Gojobori T, Munday PL, Ravasi T.

Mol Ecol Resour. 2018 Sep 10. doi: 10.1111/1755-0998.12939

Atlas of Circadian Metabolism Reveals System-wide Coordination and Communication between Clocks.

Dyar KA, Lutter D, Artati A, Ceglia NJ, Liu Y, Armenta D, Jastroch M, Schneider S, de Mateo S, Cervantes M, Abbondante S, Tognini P, Orozco-Solis R, Kinouchi K, Wang C, Swerdloff R, Nadeef S, Masri S, Magistretti P, Orlando V, Borrelli E, Uhlenhaut NH, Baldi P, Adamski J, Tschöp MH, Eckel-Mahan K, Sassone-Corsi P.

Cell. 2018 Sep 6;174(6):1571-1585.e11. doi: 10.1016/j.cell.2018.08.042.

Chemistry meets epigenetics: from chromatin tools to small molecules affecting the readout of our genomes.

Fischle W, Schwarzer D.

Curr Opin Chem Biol. 2018 Aug;45:vii-ix. doi: 10.1016/j.cbpa.2018.07.024.

The epigenetic landscape of transgenerational acclimation to ocean warming.

Ryu T, Veilleux H, Donelson J, Munday P, Ravasi T.

Nature Climate Change 2018, 8, 504-509

DeepSimulator: a deep simulator for Nanopore sequencing

Yu Li, Renmin Han, Chongwei Bi, Mo Li, Sheng Wang, Xin Gao

Bioinformatics, Volume 34, Issue 17, 1 September 2018

How Polycomb-Mediated Cell Memory Deals With a Changing Environment: Variations in PcG complexes and proteins assortment convey plasticity to epigenetic regulation as a response to environment. Marasca F, Bodega B, Orlando V.

Bioessays. 2018 Apr;40(4):e1700137. doi: 10.1002/bies.201700137. Epub 2018 Mar 9.

An interplay between plasticity and parental phenotype determines impacts of ocean acidification on a reef fish.

Schunter C, Welch MJ, Nilsson GE, Rummer JL, Munday PL, Ravasi T.

Nat Ecol Evol. 2018 Feb;2(2):334-342

Gathering by the Red Sea highlights links between environment and epigenetics.

Li M, Borrelli E, Magistretti PJ, Izpisua Belmonte JC, Sassone-Corsi P, Orlando V.

Nat Struct Mol Biol. 2017 Jun 6;24(6):491-493.

A cytosolic Ezh1 isoform modulates a PRC2-Ezh1 epigenetic adaptive response in postmitotic cells.

Bodega B, Marasca F, Ranzani V, Cherubini A, Della Valle F, Neguembor MV, Wassef M, Zippo A, Lanzuolo C, Pagani M, Orlando V.

Nat Struct Mol Biol. 2017 May;24(5):444-452.

Molecular signatures of transgenerational response to ocan acidification in a species of reef fish.

Schunter C, Welch M, Ryu, Zhang H, Berumen, M, Nilsson G, Munday P, Ravasi T.

Nature Climate Change 2016, 6, 1014-1018

Oxidative stress signaling to chromatin in health and disease.

Kreuz S, Fischle W.

Epigenomics. 2016 Jun;8(6):843-62. doi: 10.2217/epi-2016-0002. Epub 2016 Jun 20. Review.